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Neuroimmune Phenotyping as the Next Frontier in Chronic Pain Medicine for Musculoskeletal Back Pain

Curr Pain Headache Rep. 2026 Sep 5;30(1):119. doi: 10.1007/s11916-026-01561-w. ABSTRACT BACKGROUND: Chronic low back pain encompasses heterogeneous mechanical, neuropathic, nociplastic, and myofascial presentations that may reflect distinct neuroimmune mechanisms. We synthesized evidence linking these phenotypes to measurable biological features and clinically relevant treatment strategies. METHODS: We conducted a structured literature search of MEDLINE, Scopus, Web […]

Electroacupuncture promotes the repair of lacrimal glands damage in dry-eye animal models by modulating the BDNF/CREB signaling pathway

J Tradit Complement Med. 2025 Aug 27;16(5):480-491. doi: 10.1016/j.jtcme.2025.08.002. eCollection 2026 Sep. ABSTRACT BACKGROUND AND AIM: Dry eye disease (DED) is an eye disorder with global prevalence. Its treatment using electroacupuncture (EA) has shown exceptional clinical efficacy. This study aimed to examine the effectiveness of EA in treating DED and explore its underlying molecular mechanisms. […]

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