Comparing fractional CO2 laser and needling-based modalities in facial acne scar treatment: a comprehensive systematic review and meta-analysis

Lasers Med Sci. 2026 Jun 23;41(1):124. doi: 10.1007/s10103-026-04905-5. ABSTRACT Facial acne scarring is a widely prevalent dermatological disease manifested as a permanent aftereffect of acne vulgaris. While fractional CO₂ laser and needling procedures are essential to treating atrophic acne scars, comparative and safety data remains limited. This systematic review and meta-analysis directly compares their efficacy […]