This article by Roy et. al provides a very interesting viewpoint on the management of musculoskeletal disorders that traditionally focus on the structural dysfunctions found within the musculoskeletal system, mainly around the affected joint or as we call it a symptomatic point. While a structural-dysfunction approach maybe effective for musculoskeletal conditions, especially in acute presentations, its effectiveness remains limited in patients with recurrent or chronic musculoskeletal pain. This relates directly to a neurological treatment model to address the 3 S’s (symptomatic, segmental and systemic) and the 3I’s (inflammation, irritation, inhibition) of neuromusculoskeletal dysfunction. Enjoy!