Identifying Early Responders to Dry Needling for Lower-Limb Spasticity in Multiple Sclerosis: A Secondary Responder Analysis of a Pilot Randomized Controlled Trial

Brain Sci. 2026 Feb 21;16(2):240. doi: 10.3390/brainsci16020240. ABSTRACT Background/Objectives: Response heterogeneity limits the implementation of dry needling for spasticity in multiple sclerosis (MS). This secondary analysis aimed to identify early responders and explore predictors of response. Methods: We conducted a responder analysis of a pilot randomized, double-blind, sham-controlled trial (NCT05956119) including 18 ambulatory MS patients […]