Clinical efficacy of 5-aminolevulinic acid photodynamic therapy combined with microneedling for vulvar lichen sclerosus

Photodiagnosis Photodyn Ther. 2025 Jun;53:104623. doi: 10.1016/j.pdpdt.2025.104623. Epub 2025 May 8. ABSTRACT BACKGROUND: Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis with limited therapeutic options for refractory or recurrent cases. This study aimed to evaluate the efficacy and safety of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with microneedling in VLS management. METHODS: Sixty-four VLS […]

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